Microfabricating high-aspect-ratio structures in polyurethane-methacrylate (PUMA) disposable microfluidic devices.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19532971.
- Also identified by DOI 10.1039/b902124h and PMC identifier 5600469.
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Abstract
We recently reported a new UV-curable polyurethane-methacrylate (PUMA) resin that has excellent qualities as a disposable microfluidic substrate for clinical diagnostic applications. This article discusses strategies to improve the production yield of PUMA chips that contain dense and high-aspect-ratio features, which presents unique challenges in demolding and bonding steps. These fabrication improvements were deployed to produce a microfiltration device that contained closely spaced and high-aspect-ratio columns, suitable for retaining and concentrating cells or beads from a highly diluted suspension.
Medical subject headings
- Methacrylates
- Microfluidic Analytical Techniques
- Micropore Filters
- Polyurethanes