The cell cycle and acute kidney injury.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19536080.
- Also identified by DOI 10.1038/ki.2009.224 and PMC identifier 2782725.
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Abstract
Acute kidney injury (AKI) activates pathways of cell death and cell proliferation. Although seemingly discrete and unrelated mechanisms, these pathways can now be shown to be connected and even to be controlled by similar pathways. The dependence of the severity of renal-cell injury on cell cycle pathways can be used to control and perhaps to prevent acute kidney injury. This review is written to address the correlation between cellular life and death in kidney tubules, especially in acute kidney injury.
Medical subject headings
- Cell Cycle
- Kidney