A retrospective evaluation of completion rates, total cost, and adverse effects for treatment of latent tuberculosis infection in a public health clinic in central massachusetts.

Young, Heather; Wessolossky, Mireya; Ellis, Jeanne; Kaminski, Martin; Daly, Jennifer S · Clin Infect Dis · 2009

retrospective_cohort · Level III

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Abstract

Completion rates, total cost, and adverse effects were compared for patients in central Massachusetts treated for latent tuberculosis infection with 9 months of isoniazid or 4 months of rifampin. Although the adverse effects were similar between the 2 groups, 4 months of rifampin was associated with significantly better completion rates and less hepatotoxicity yet higher total cost.

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