Fluconazole failure in the treatment of invasive mycoses.

Evans, T G; Mayer, J; Cohen, S; Classen, D; Carroll, K · J Infect Dis · 1991

case_report · Level V

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Abstract

Fluconazole is a recently licensed antifungal agent that has gained widespread use in the medical community. Despite a lack of controlled trials in invasive fungal infections, this agent is often prescribed because of ease of administration and concern over amphotericin B toxicity. Three cases of systemic fungal infections in which fluconazole use resulted in unambiguous microbiologic and clinical failure are reported.

Medical subject headings