Ironing out a midlife crisis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19563748.
- Also identified by DOI 10.1016/j.cell.2009.06.005.
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Abstract
There is a strong correlation between age, genomic instability, and the development of cancer. Working in yeast, Veatch et al. (2009) now propose that defects in the biogenesis of iron-sulfur clusters arising as a consequence of mitochondrial dysfunction contribute to the increase in genomic instability as cells age.
Medical subject headings
- Iron
- Saccharomyces cerevisiae