Effects of single dose irradiation on pancreatic beta-cell function.

Sarri, Y; Conill, C; Verger, E; Tomas, C; Gomis, R · Radiother Oncol · 1991

basic_science · Level V

Where this comes from

Abstract

We have irradiated abdominal cavity of 23 rats with 10 Gy irradiation-induced hypoglycemia on the fourth day after intervention. Islets collected at this time showed an impaired insulin secretion without affecting insulin content. This impairment persisted after one month follow-up with reduced number of beta-cells in morphological examination.

Medical subject headings