gPS navigates germ cells to pluripotency.

Geijsen, Niels; Hochedlinger, Konrad · Cell Stem Cell · 2009

editorial · Level V

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Abstract

The establishment of pluripotent stem cell lines from explanted testes has been hampered by a poor understanding of their cellular origin. In this issue of Cell Stem Cell, Ko et al. (2009) reproducibly generate pluripotent cell lines from murine testes and unequivocally demonstrate their origin from spermatogonial stem cells.

Medical subject headings