Revealing tumor immunity after hematopoietic stem cell transplantation.

Wu, Catherine J; Ritz, Jerome · Clin Cancer Res · 2009

editorial · Level V

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Abstract

Allogeneic hematopoietic stem cell transplantation is currently the most effective method for inducing tumor immunity. However, the diversity of target antigens recognized by donor T cells has not been established. New studies show that tumor-reactive T cells are directed against diverse tumor-specific targets as well as minor histocompatibility antigens.

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