Dexamethasone in Cryptococcus gattii central nervous system infection.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 19589083.
- Also identified by DOI 10.1086/603554.
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Abstract
Clinical outcomes were reviewed for 4 patients with Cryptococcus gattii central nervous system infection who received dexamethasone for the treatment of persisting mental status abnormalities and focal lesions on brain scan despite culture-negative cerebrospinal fluid and the management of intracranial pressure. Favorable clinical responses were observed in 3 patients. Although corticosteroids are not recommended for the treatment of cryptococcal meningitis, these observations suggest that dexamethasone should be further evaluated in this subset of patients.
Medical subject headings
- Anti-Inflammatory Agents
- Central Nervous System Infections
- Cryptococcosis
- Cryptococcus
- Dexamethasone