Mechanical interferometry of nanoscale motion and local mechanical properties of living zebrafish embryos.

Reed, Jason; Ramakrishnan, Siddarth; Schmit, Joanna; Gimzewski, James K · ACS Nano · 2009

basic_science · Level V

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Abstract

We present an interferometric imaging technique that permits local measurement of mechanical properties and nanomechanical motion in small living animals. Measurements of nanomechanical properties and spatially resolved pulsations of <60 nm were recorded for the developing eye of a living zebrafish (Danio rerio) embryo, an important model organism. We also used magnetic microreflectors to conduct contact nanomechanical indentation measurements of the stiffness of the embryonic eye.

Medical subject headings