Getting to first base in proteasome assembly.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19596233.
- Also identified by DOI 10.1016/j.cell.2009.06.035 and PMC identifier 3824964.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Assembly of complex structures such as the eukaryotic 26S proteasome requires intricate mechanisms that ensure precise subunit arrangements. Recent studies have shed light on the pathway for ordered assembly of the base of the 19S regulatory particle of the 26S proteasome by identifying new precursor complexes and four dedicated chaperones involved in its assembly.
Medical subject headings
- Proteasome Endopeptidase Complex