Whipple disease of the central nervous system: an unusual occurrence in association with acquired immune deficiency syndrome.

Guthikonda, Bharat; Rouah, Emilie; Krishnan, Bhuvanaswari; Powell, Suzanne Z; Goodman, J Clay; Gopinath, Shankar P; Simpson, Richard K · J Neurosurg · 2010

case_report · Level V

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Abstract

Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.

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