Vascular perfusion abnormalities in infants with spinal muscular atrophy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19619755.
- Also identified by DOI 10.1016/j.jpeds.2009.01.071 and PMC identifier 3250227.
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Abstract
Spinal muscular atrophy (SMA) is an important cause of death in children and SMA type I, also known as Werdnig-Hoffman disease, is the most severe form of this disease. We report 2 cases of infants with SMA I in whom a distal necrosis developed, a feature not previously reported. Poor perfusion, autonomic dysfunction, and position-dependent factors may all play a role in the development of this complication.
Medical subject headings
- Fingers
- Spinal Muscular Atrophies of Childhood
- Toes