Pregabalin: a new approach to treatment of the dysautonomic crisis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 19620195.
- Also identified by DOI 10.1542/peds.2008-3318.
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Abstract
Nausea and dysautonomic crises severely limit function and quality of life for a large number of individuals with familial dysautonomia. We treated a small cohort of 15 patients with familial dysautonomia who suffered frequent dysautonomic crises with pregabalin. Nausea and overt crises markedly decreased in 13 (87%) of these patients and the overall assessments of benefit were extremely favorable, suggesting that pregabalin may be a potentially useful therapeutic agent for this disorder.
Medical subject headings
- Anticonvulsants
- Dysautonomia, Familial
- gamma-Aminobutyric Acid