Stressing out over tRNA cleavage.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19632169.
- Also identified by DOI 10.1016/j.cell.2009.07.001.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A conserved response to stress involves endonucleolytic cleavage of cytoplasmic transfer RNAs (tRNAs) by ribonucleases that are normally secreted or sequestered. Ribonuclease activation or release is an intriguing new aspect of cellular stress responses, with a potential impact on translation, apoptosis, cancer, and disease progression.
Medical subject headings
- Cell Physiological Phenomena
- RNA, Transfer