RIP kinases at the crossroads of cell death and survival.

Declercq, Wim; Vanden Berghe, Tom; Vandenabeele, Peter · Cell · 2009

basic_science · Level V

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Abstract

Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor proteins to regulate cell death. Recent studies (Cho et al., 2009; He et al., 2009; Zhang et al., 2009) reveal that the RIP3 kinase functions with RIP1 at the crossroads of apoptosis, necroptosis, and cell survival.

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