Comment on "Remeasuring the double helix".
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19644093.
- Also identified by DOI 10.1126/science.1168786.
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Abstract
Mathew-Fenn et al. (Reports, 17 October 2008, p. 446) reported unexpected distance fluctuations in short end-labeled DNA constructs and interpreted them as evidence for cooperative DNA stretching modes. We show that when accounting for a subtle linker leverage effect, their data can be understood within standard noncooperative DNA elasticity.
Medical subject headings
- DNA
- Nucleic Acid Conformation