Genoscape: a Cytoscape plug-in to automate the retrieval and integration of gene expression data and molecular networks.

Clément-Ziza, Mathieu; Malabat, Christophe; Weber, Christian; Moszer, Ivan; Aittokallio, Tero; Letondal, Catherine; Rousseau, Sandrine · Bioinformatics · 2009

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Abstract

Genoscape is an open-source Cytoscape plug-in that visually integrates gene expression data sets from GenoScript, a transcriptomic database, and KEGG pathways into Cytoscape networks. The generated visualisation highlights gene expression changes and their statistical significance. The plug-in also allows one to browse GenoScript or import transcriptomic data from other sources through tab-separated text files. Genoscape has been successfully used by researchers to investigate the results of gene expression profiling experiments. Genoscape is an open-source software freely available from the Genoscape webpage (http://www.pasteur.fr/recherche/unites/Gim/genoscape/). Installation instructions and tutorial can also be found at this URL.

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