Alpha cells beget beta cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19665963.
- Also identified by DOI 10.1016/j.cell.2009.07.022.
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Abstract
Understanding the origins of insulin-producing beta cells of the pancreas could lead to new treatments for diabetes. Collombat et al. (2009) now show that in response to injury, a population of pancreatic progenitor cells can give rise to glucagon-expressing alpha cells that then transdifferentiate into beta cells.
Medical subject headings
- Glucagon-Secreting Cells
- Insulin-Secreting Cells
- Pancreas