Compression strength and porosity of single-antibiotic cement vacuum-mixed with vancomycin.
biomechanical · Level V
Where this comes from
- Record sourced from PubMed, PMID 19679443.
- Also identified by DOI 10.1016/j.arth.2009.06.027.
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Abstract
We evaluated the ultimate compression strength (UCS), porosity, and fracture surface roughness of 2 commercially available single-antibiotic bone cements vacuum-mixed with additional amounts of vancomycin (2, 4, 6, and 8 g). At least 8 g could be added to Palacos R + 0.5 g gentamicin (UCS = 75.04 +/- 6.64 MPa) and no more than 6 g to Simplex P + 1 g tobramycin (UCS = 78.93 +/- 4.98 MPa) to maintain a UCS above the International Organization for Standardization minimum standard (70 MPa). Increasing vancomycin concentration correlated with a decrease in porosity but showed a trend towards greater fracture surface roughness.
Medical subject headings
- Arthroplasty, Replacement
- Bone Cements
- Vancomycin