The pathobiology of HIV infection. A review.

Smith, R D · Arch Pathol Lab Med · 1990

review · Level V

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Abstract

Human immunodeficiency virus selectively infects lymphocytes and macrophages resulting in profound immunosuppression leading to opportunistic infections. This review deals with the virus/cell interaction and explains the apparent paradox of the global immune defect in the acquired immunodeficiency syndrome of a single subset of lymphocytes.

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