Trial of fluoxetine added to neuroleptics for treatment-resistant schizophrenic patients.

Goff, D C; Brotman, A W; Waites, M; McCormick, S · Am J Psychiatry · 1990

prospective_cohort · Level II

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Abstract

Mean ratings of positive and negative symptoms and depression significantly improved in nine treatment-resistant schizophrenic patients who completed a 6-week open trial of fluoxetine added to their neuroleptics. The authors identify differences between responders and nonresponders and recommend controlled trials.

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