Effect of imipramine on depression and immune status in a sample of men with HIV infection.

Rabkin, J G; Harrison, W M · Am J Psychiatry · 1990

case_series · Level IV

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Abstract

Eleven men with major depression and human immunodeficiency virus (HIV) infection underwent an open trial of imipramine. Eight of nine (89%) who completed 12 weeks responded. The mean decline in T4 cells from baseline was 100 at week 12 and 16 at week 26. No major exacerbations of HIV infection occurred.

Medical subject headings