Clinical practice. Infection associated with prosthetic joints.

Del Pozo, Jose L; Patel, Robin · N Engl J Med · 2009

review · Level V

Where this comes from

Abstract

A 62-year-old woman with osteoarthritis presents with a 7-month history of progressively worsening left hip pain radiating to the groin, 8 months after undergoing total left-hip arthroplasty. The pain has not responded to nonsteroidal antiinflammatory drugs. Physical examination reveals a sinus tract overlying her left hip. Her leukocyte count is 8000 per cubic millimeter, and the C-reactive protein (CRP) level is 15.5 mg per liter. A radiograph shows loosening of the prosthesis at the bone–cement interface. Synovial-fluid aspirate shows 15×10<sup>3</sup> cells per cubic millimeter (89% neutrophils); cultures of an aspirate from the hip grow <i>Staphylococcus epidermidis</i>. How should her case be managed?

Medical subject headings

Anatomy