WNTs tune up the neuromuscular junction.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19693027.
- Also identified by DOI 10.1038/nrn2681 and PMC identifier 3499984.
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Abstract
Although WNTs have been long thought of as regulators of cell fate, recent studies highlight their involvement in crucial aspects of synaptic development in the nervous system. Particularly compelling are recent studies of the neuromuscular junction in nematodes, insects, fish and mammals. These studies place WNTs as major determinants of synapse differentiation and neurotransmitter receptor clustering.
Medical subject headings
- Neuromuscular Junction
- Synapses
- Wnt Proteins