Normalization of diabetic wound healing.

Francis-Goforth, Kellie N; Harken, Alden H; Saba, Julie D · Surgery · 2010

review · Level V

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Abstract

Impaired wound healing in diabetics is due to pathologic angiogenesis, which is a result of aberrant sphingosine-1-phosphate signaling. Pharmacologic modulation of sphingosine-1-phosphate-dependent signaling normalizes healing in diabetic wounds.

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