Blood flow-metabolism mismatch: good for the tumor, bad for the patient.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19706819.
- Also identified by DOI 10.1158/1078-0432.CCR-09-1448 and PMC identifier 2941711.
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Abstract
While tightly coupled in most normal tissues, blood flow and metabolism are often not well matched in tumors. A flow-metabolism mismatch, specifically high metabolism relative to blood flow, can be recognized in tumors by functional and molecular imaging and is associated with poor response to treatment and early relapse or disease progression.
Medical subject headings
- Glucose
- Pancreatic Neoplasms
- Regional Blood Flow