Stem cells: The promises and perils of p53.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19713919.
- Also identified by DOI 10.1038/4601085a and PMC identifier 2974062.
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Abstract
Five studies show that disabling p53, an essential tumour-suppressor protein, improves the efficiency of stem-cell production. Are these results a ‘heads up’ that cancer cells and stem cells are disturbingly similar?
Medical subject headings
- Cellular Reprogramming
- Pluripotent Stem Cells
- Tumor Suppressor Protein p53