Bile acids have the gall to function as hormones.

Vallim, Thomas Quad de Aguiar; Edwards, Peter A · Cell Metab · 2009

editorial · Level V

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Abstract

In this issue of Cell Metabolism, Thomas et al. (2009) show that specific activation of the bile-acid-activated G protein-coupled receptor TGR5 improves pancreatic and hepatic function and impairs the development of obesity following administration of a high-fat diet.

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