Lineage commitment: cytokines instruct, at last!
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19733531.
- Also identified by DOI 10.1016/j.stem.2009.08.015 and PMC identifier 4049006.
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Abstract
Instructive and permissive models of commitment have been proposed for hematopoietic cytokines. In recent issues of Science and Cell, Rieger et al. (2009) and Sarrazin et al. (2009) together show that cytokines can instruct lineage choice.
Medical subject headings
- Animals
- Cell Differentiation
- Cell Lineage
- Cytokines
- Cytokines/metabolism
- Humans
- MafB Transcription Factor
- MafB Transcription Factor/metabolism
- Mice
- Models, Biological
- Multipotent Stem Cells
- Multipotent Stem Cells/cytology
- Multipotent Stem Cells/metabolism