Pluripotent stem cells and disease modeling.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19733533.
- Also identified by DOI 10.1016/j.stem.2009.08.010.
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Abstract
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease.
Medical subject headings
- Animals
- Disease
- Disease Models, Animal
- Embryonic Stem Cells
- Embryonic Stem Cells/cytology
- Humans
- Models, Biological
- Pluripotent Stem Cells
- Pluripotent Stem Cells/cytology