IKKepsilon: a bridge between obesity and inflammation.

Olefsky, Jerrold M · Cell · 2009

review · Level V

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Abstract

Obesity leads to tissue inflammation and insulin resistance, which are features of metabolic diseases such as type 2 diabetes. Chiang et al. (2009) now show that the IkappaB kinase IKKepsilon is an important link between obesity and inflammation and may be a new therapeutic target for treating obesity-related metabolic diseases.

Medical subject headings