A neural network critical for spelling.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 19743449.
- Also identified by DOI 10.1002/ana.21693 and PMC identifier 2745512.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We aimed to identify neuroanatomical regions associated with deficits to the graphemic buffer, a working memory component of the spelling system that holds the sequence of letter identities during production. We evaluated 331 patients with left hemisphere ischemic stroke with various spelling tests and magnetic resonance diffusion-weighted imaging and perfusion-weighted imaging, within 48 hours of stroke onset. A voxel-wise statistical map showed that ischemia in voxels in posterior and inferior frontal and parietal cortex, subcortical white matter underlying prefrontal cortex, lateral occipital gyrus, or caudate was associated with impairment in maintaining the sequence of letter identities while spelling.
Medical subject headings
- Brain
- Brain Ischemia
- Linguistics
- Memory, Short-Term
- Stroke
- Writing