The pharmacology of new anxiolytics acting on 5-HT neurones.
review · Level V
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Abstract
This paper discusses the alternative approaches available for the development of anxiolytics not acting on the benzodiazepine--GABA receptor complex. There are now several compounds that work by reducing 5-hydroxytryptamine function in the brain that have been shown to have anxiolytic properties in animals and in some cases man. Detailed long-term clinical trials are required to determine whether these new drugs are clinically useful and avoid the problems associated with benzodiazepines.
Medical subject headings
- Anti-Anxiety Agents
- Neurons
- Receptors, Serotonin