Polymer-supported lipid shells, onions, and flowers.

Bershteyn, Anna; Chaparro, José; Yau, Richard; Kim, Mikyung; Reinherz, Ellis; Ferreira-Moita, Luis; Irvine, Darrell J · Soft Matter · 2008

basic_science · Level V

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Abstract

Phospholipid-enveloped biodegradable polymer microparticles and nanoparticles synthesized by an emulsion/solvent evaporation process were characterized by confocal and cryoelectron microscopies to show that the lipid envelope exhibits two-dimensional fluidity and can be configured into 'shell', 'onion', or 'flower' nanostructures, depending on the quantity and composition of lipids employed in the synthesis.