Biperiden and piroheptine do not affect the serum level of zotepine, a new antipsychotic drug.
case_series · Level IV
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Abstract
The effects of biperiden and piroheptine on the serum level of zotepine were studied in 15 schizophrenic and 6 mentally retarded in-patients. Neither of these anticholinergic drugs affected the serum level of zotepine nor caused significant side-effects. In the schizophrenics the total scores on the BPRS did not change significantly with either combination of drugs.
Medical subject headings
- Antipsychotic Agents
- Biperiden
- Dibenzocycloheptenes
- Dibenzothiepins
- Intellectual Disability
- Piperidines
- Pyrrolidines
- Schizophrenia
- Schizophrenic Psychology