Comment on "The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles".
editorial · Level V
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- Record sourced from PubMed, PMID 19762627.
- Also identified by DOI 10.1126/science.1175790.
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Abstract
Zhang et al. (Research Articles, 13 March 2009, p. 1448) reported that synaptic vesicles usually release neurotransmitter through a kiss-and-run mechanism occurring within 1 second but that full collapse of the vesicles becomes more prevalent with repeated stimuli. We report that the kinetics of vesicle retrieval do not change during a stimulus train, with endocytosis occurring in 10 to 15 seconds.
Medical subject headings
- Endocytosis
- Neurotransmitter Agents
- Quantum Dots
- Synapses
- Synaptic Transmission
- Synaptic Vesicles