p53: a new kingpin in the stem cell arena.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19766559.
- Also identified by DOI 10.1016/j.cell.2009.09.004.
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Abstract
Identifying new regulators of the stem cell state offers potential for future gains in biomedicine. Evidence that the tumor suppressor p53 is a key regulator of the stem cell state (Cicalese et al., 2009) suggests a broad role for this protein and its pathways in the control of normal tissue homeostasis and tumor formation.
Medical subject headings
- Neoplastic Stem Cells
- Tumor Suppressor Protein p53