Reducing the mystery of neuronal differentiation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19766560.
- Also identified by DOI 10.1016/j.cell.2009.09.001.
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Abstract
In the developing nervous system, neural progenitors exit the cell cycle and differentiate on a precise schedule, yet the mechanisms driving this process remain poorly defined. Yan et al. (2009) now identify a thiol-redox reaction mediated by the membrane protein GDE2 and the peroxiredoxin protein Prdx1 that promotes neurogenesis.
Medical subject headings
- Neurons
- Spinal Cord