New treatment with human atrial natriuretic peptide for postoperative myonephropathic metabolic syndrome.

Sezai, Akira; Hata, Mitsumasa; Niino, Tesuya; Yoshitake, Isamu; Unosawa, Satoshi; Umezawa, Hisaki; Minami, Kazutomo · Ann Thorac Surg · 2009

case_report · Level V

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Abstract

A 49-year-old man had sudden chest pain and paralysis of the lower right limb. An acute aortic dissection was diagnosed in a computed tomography scan and the patient underwent an emergency operation. After the operation, myonephropathic metabolic syndrome developed, and human atrial natriuretic peptide was administered for 11 days until the volume of daily urine output reached at least 10,000 mL, which would facilitate limb salvage and the preservation of life without hemodialysis. This report documents that postoperative myonephropathic metabolic syndrome improved due to the strong diuretic action of human atrial natriuretic peptide without hemodialysis.

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