MOODS: fast search for position weight matrix matches in DNA sequences.

Korhonen, Janne; Martinmäki, Petri; Pizzi, Cinzia; Rastas, Pasi; Ukkonen, Esko · Bioinformatics · 2009

basic_science · Level V

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Abstract

MOODS (MOtif Occurrence Detection Suite) is a software package for matching position weight matrices against DNA sequences. MOODS implements state-of-the-art online matching algorithms, achieving considerably faster scanning speed than with a simple brute-force search. MOODS is written in C++, with bindings for the popular BioPerl and Biopython toolkits. It can easily be adapted for different purposes and integrated into existing workflows. It can also be used as a C++ library. The package with documentation and examples of usage is available at http://www.cs.helsinki.fi/group/pssmfind. The source code is also available under the terms of a GNU General Public License (GPL).

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