Prolonged neuromuscular blockade with vecuronium in a neonate with renal failure.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 1978607.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
An 11-day-old neonate with renal failure caused by dysplastic kidneys was anaesthetised with thiopentone, vecuronium, nitrous oxide and oxygen, for insertion of a long-term peritoneal dialysis catheter. Complete neuromuscular block of 210 minutes' duration ensued after the initial dose of vecuronium (97 micrograms/kg). Partial block persisted for a further 30 minutes. The prolonged neuromuscular block in this case may have been because of proportionately greater dependence on renal clearance of vecuronium in neonates.
Medical subject headings
- Kidney
- Kidney Failure, Chronic
- Neuromuscular Junction
- Vecuronium Bromide