Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement.

Randelli, Pietro; Evola, Francesco R; Cabitza, Paolo; Polli, Luca; Denti, Matteo; Vaienti, Luca · Knee Surg Sports Traumatol Arthrosc · 2010

review · Level V

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Abstract

Despite significant advances in intraoperative antimicrobial procedures, deep infection remains the most devastating complication following total joint arthroplasty. Clinical studies' results and safety profile of antibiotic-loaded bone cement are discussed in this review. Antibiotic bone cement prophylaxis is a safe and effective strategy in reducing the risk of deep infection following primary total joint arthroplasty.

Medical subject headings

Anatomy