Oxysterols drive dopaminergic neurogenesis from stem cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19796609.
- Also identified by DOI 10.1016/j.stem.2009.09.001 and PMC identifier 6188706.
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Abstract
Stem cell therapy for Parkinson's disease requires effective production of dopaminergic neurons. In this issue of Cell Stem Cell, Sacchetti et al. (2009) report an unexpected role of liver X receptors and their ligand, oxysterols, in regulating dopaminergic neurogenesis.
Medical subject headings
- Cholesterol
- Dopamine
- Embryonic Stem Cells
- Mesencephalon
- Neurogenesis