Processing and population genetic analysis of multigenic datasets with ProSeq3 software.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19797407.
- Also identified by DOI 10.1093/bioinformatics/btp572 and PMC identifier 2778335.
- Licence recorded as CC BY-NC.
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Abstract
The current tendency in molecular population genetics is to use increasing numbers of genes in the analysis. Here I describe a program for handling and population genetic analysis of DNA polymorphism data collected from multiple genes. The program includes a sequence/alignment editor and an internal relational database that simplify the preparation and manipulation of multigenic DNA polymorphism datasets. The most commonly used DNA polymorphism analyses are implemented in ProSeq3, facilitating population genetic analysis of large multigenic datasets. Extensive input/output options make ProSeq3 a convenient hub for sequence data processing and analysis. The program is available free of charge from http://dps.plants.ox.ac.uk/sequencing/proseq.htm.
Medical subject headings
- Computational Biology
- Genetics, Population
- Software