Condensin(g) crossover control to a few breaks.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19804748.
- Also identified by DOI 10.1016/j.cell.2009.09.016.
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Abstract
Meiotic chromosome pairs must receive at least one crossover to ensure proper segregation at the first meiotic division. Mets and Meyer (2009) now present compelling evidence that the establishment of higher-order chromosome structure by a condensin complex regulates crossover recombination by controlling the distribution and frequency of meiotic double-strand breaks.
Medical subject headings
- Adenosine Triphosphatases
- Caenorhabditis elegans Proteins
- Crossing Over, Genetic
- DNA-Binding Proteins
- Multiprotein Complexes