Leptin's RIGHT turn to the brain stem.

Rosen, Clifford J · Cell Metab · 2009

Level V

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Abstract

In a paper by Yadav and colleagues, a novel pathway linking the central nervous system effects of leptin on bone mass and energy expenditure to serotonin signaling in brainstem circuits is described. The data from those studies strengthen the tenet that skeletal remodeling is intimately connected to central regulation of metabolism.

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