Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 19814625.
- Also identified by DOI 10.1086/630207 and PMC identifier 4340500.
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Abstract
Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal fluid (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved and levels of CSF cytokines interleukin (IL)-6, IL-8, and IL-10 and were all statistically significantly lower after treatment in patients who were randomized to dexamethasone, compared with levels in patients who received placebo.
Medical subject headings
- Dexamethasone
- Meningitis, Bacterial