Outcome domains for studies of acute and chronic gout.

Schumacher, H Ralph; Taylor, William; Edwards, Lawrence; Grainger, Rebecca; Schlesinger, Naomi; Dalbeth, Nicola; Sivera, Francisca; Singh, Jasvinder et al. · J Rheumatol · 2009

review · Level V

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Abstract

Discussion and voting at OMERACT 9 confirmed 5 essential domains for outcomes of acute gout: pain, joint swelling, joint tenderness, patient global assessment and activity limitations. For studies in chronic gout 7 essential domains are: serum urate, acute gout attacks, tophus burden, health-related quality of life, activity limitations, pain, and patient global assessment. Implications of patient perspectives, discretionary domains for specific studies, measurement instruments and a possible responder index are under study.

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