Optical signal comparison of single fluorescent molecules and Raman active gold nanostars.
basic_science · Level V
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- Record sourced from PubMed, PMID 19827758.
- Also identified by DOI 10.1021/nl902008g.
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Abstract
The relevant photophysical properties of single fluorescent molecules and single SERS active surface-coated gold nanostars tagged with the Raman reporter molecule 4-mercaptopyridine are compared for imaging purposes. Mean count rate distributions are built from the single molecule/single probe level. The individually observed variance and count rates of both systems are compared as well as the behavior over multiple image acquisitions.